Here’s some recent work on it:
- “Sesame oil(SO) research shows promise in decreasing high levels of cholesterol and inflammation, lowering risks of atherosclerosis, and delaying the onset of cardiovascular diseases.
- Since SO is very inexpensive and natural, progressing research on SO to someday implement SO as a good pharmaceutical treatment would be an investment, especially when SO has yet to show adverse effects. However, SO has not had many clinical trials, and the benefits relative to other oils and medications still need to be investigated. This literature review found that the benefits of SO vary between studies due to the methodology of SO product, dose dependence, and examination of different variables.
- Many of these studies are limited because they do not isolate the benefit of SO in humans alone and because there are different concentrations of SO used in each study. Future studies should examine the different concentrations of SO and its effects on humans with hyperlipidemia, hypertension, and diabetes mellitus in a dose-dependent manner relative to the patient’s body habitus.
- Future studies can also look at synergism by comparing patients treated with differing combinations of medication, such as nifedipine, statins, metformin, with different concentrations of SO relative to the individual’s saturated fat diet.”
Source: NCBI :”Anti-inflammatory and Antioxidant Effects of Sesame Oil on Atherosclerosis: A Descriptive Literature Review” Editors:Alexander Muacevic and John R Adler.
Another study:
- “Sesame ingestion significantly decreased concentrations of plasma TC by 5% and LDL-C by 10%
- Sesame lignans were found to have a γ-tocopherol sparing effect by inhibiting CYP activity. Our study showed increased serum levels of γ-tocopherol, similar to 2 other trials in humans.
- The estrogenic effects of flaxseed lignans in postmenopausal women include decreasing plasma levels of estrone sulfate and estradiol (39) and switching estrogen metabolism from 16α-hydroxylation to a less carcinogenic pathway (2-hydroxylation).”
Source: The Journal of Nutrition: “Sesame Ingestion Affects Sex Hormones, Antioxidant Status, and Blood Lipids in Postmenopausal Women” by